C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 417/12 (2006.01) A61K 31/427 (2006.01) C07D 417/14 (2006.01)
Patent
CA 2503715
The present invention relates to compounds which inhibit, regulate and/or modulate kinase signal transduction, compositions which contain these compounds, and methods of using them to treat kinase-dependent diseases and conditions, such as angiogenesis, cancer, tumor growth, atherosclerosis, age related macular degeneration, retinal ischemia, macular edema, diabetic retinopathy, inflammatory diseases, and the like in mammals.
La présente invention concerne des composés qui inhibent, régulent et/ou modulent la traduction du signal de la kinase, des compositions contenant ces composés et, des techniques d'utilisation de ces compositions pour traiter des maladies et des pathologies dépendant de la kinase, telles que l'angiogenèse, le cancer, la croissance tumorale, l'athérosclérose, la dégénération maculaire liée à l'âge, l'ischémie rétinienne, l'oedème maculaire, la rétinopathie diabétique, des maladies inflammatoires et d'autres maladies similaires chez les mammifères.
Hartman George D.
Hoffman Jacob M.
Smith Anthony M.
Tucker Thomas J.
Merck & Co. Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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