Kinase inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 403/14 (2006.01) A61K 31/497 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01)

Patent

CA 2648124

Disclosed is a compound of the formula and the pharmaceutically acceptable salts thereof. Also disclosed are methods of treating protein kinase mediatied diseases using the compound of formula (1.0). Also disclosed are methods of treating cancer using a compound of formula (1.0). The disclosed methods also include combination therapies wherein the compound of formula (1.0) is administered in combination with at least one addition pharmaceutically active ingredient.

L'invention concerne un composé de la formule (I) et ses sels pharmaceutiquement acceptables. L'invention décrit également des procédés de traitement de maladies à médiation par la protéine kinase utilisant le composé de formule 1Ø L'invention concerne également des procédés de traitement du cancer à l'aide d'un composé de formule 1Ø Les procédés concernés comprennent également des thérapies combinatoires dans lesquelles le composé de formule 1.0 est administré en combinaison avec un ingrédient pharmaceutiquement actif d'addition au moins.

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