Kinase inhibitors, compositions comprising them, and methods...

Details Kinase inhibitors, compositions comprising them, and methods... Kinase inhibitors, compositions comprising them, and methods...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2695857

Inhibitors of LIM kinase 2 are disclosed, along with pharmaceutical compositions com .pi.sin them and methods of their use, X is O or NR A; Y is O, NR R, or C(R R)2; A is cycloalkyl, aryl or heterocycle; R A is hydrogen, cyano, nitro, R A1, SO2R A1, SO2NR A1, or SO2N(R A1)2;

La présente invention concerne des inhibiteurs de LIM kinase-2, ainsi que des compositions pharmaceutiques les contenant et des procédés permettant leur utilisation.

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