Kinase inhibitors useful for the treatment of...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 401/14 (2006.01) A61K 31/4427 (2006.01) A61K 31/4709 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2666563

The present invention is concerned with novel compounds useful in the treatment of hyperproliferative diseases and mammalian cancers, especially human cancers. The invention also pertains to methods of modulating kinase activities, pharmaceutical compositions, and methods of treating individuals, incorporating or using the compounds. The preferred compounds are active small molecules set forth in formulae Ia-Iww.

La présente invention concerne de nouveaux composés utiles pour le traitement des maladies hyperproliférantes et de cancers mammaliens, notamment de cancers humains. L'invention concerne également des procédés de modulation de l'activité de kinase, des compositions pharmaceutiques et des procédés de traitement d'individus, incorporant ou utilisant les composés. Les composés préférés sont de petites molécules actives représentées par les formules Ia-Iww.

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