Kinase wee1 fusion protein compositions, nucleotide...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/62 (2006.01) C07K 14/00 (2006.01) C07K 14/47 (2006.01) C07K 19/00 (2006.01) C12N 9/10 (2006.01) C12N 9/12 (2006.01) C12N 15/11 (2006.01) C12N 15/54 (2006.01) C12N 15/63 (2006.01) C12Q 1/48 (2006.01)

Patent

CA 2324230

The invention describes recombinant fusion proteins containing Wee1 protein sequences involved in checkpoint regulation of cell cycle, nucleic acid molecules that encode the fusion protein, and methods using the proteins for screening for compounds which modulate Wee1 or Cds1 function.

L'invention a trait à des protéines de fusion recombinées contenant des séquences de la protéine Wee1 qui interviennent dans la régulation de points de contrôle du cycle cellulaire, à des molécules d'acides nucléiques codant pour la protéine de fusion, et à des procédés utilisant les protéines pour détecter des composés qui modulent la fonction Wee1 ou Cds1.

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