Kit and method for administration of bacillus calmette-guerin

A - Human Necessities – 61 – K

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A61K 39/07 (2006.01) A61K 35/74 (2006.01) A61K 47/02 (2006.01) A61K 47/18 (2006.01) A61K 47/20 (2006.01) A61K 47/22 (2006.01)

Patent

CA 2055715

16 ABSTRACT OF THE DISCLOSURE Improved treatment of superficial bladder tumors through the administration by intravesical instillation of bacillus Calmette-Guerin is realized through the use of a therapeutic composition comprising bacillus Calmette-Guerin (BCG) suspended in an 0.85 to 0.90 wt % (i.e. about 0.15 M) sodium chloride solution containing a buffer to maintain the pH of the solution in the range 6.6 to 7.4, preferably 7Ø A kit and method are provided whereby such a composition may be employed to maximize intravesical attachment of BCG for improved efficacy.

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