A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 51/08 (2006.01) A61K 51/10 (2006.01) G01N 33/534 (2006.01)
Patent
CA 2362908
Methods and kits for radiolabeling proteins and peptides with radiolytic isotopes, particularly yttrium-90, are disclosed, whereby sufficient purity, specific activity and binding affinity are achieved such that the radiolabeled protein may be direclty administered to a patient without further column purification. Such kits and methods will be particularly useful in bringing radioimmunotherapy to the hospital and outpatient setting for the treatment of cancer.
L'invention concerne des procédés et trousses de radiomarquage de protéines et de peptides avec des isotopes radiolytiques, notamment l'yttrium-90, qui permettent d'obtenir une pureté suffisante, une activité spécifique et une affinité de liaison de façon à pouvoir administrer directement à un patient la protéine radiomarquée sans nouvelle colonne de purification. De tels trousses et procédés seront particulièrement utiles pour présenter une radioimmunothérapie en hôpital ou en consultations externes pour le traitement du cancer.
Chinn Paul
Biogen Idec Inc.
Gowling Lafleur Henderson Llp
Idec Pharmaceutical Corporation
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