A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/158, 167/199
A61K 9/12 (2006.01) A61K 31/70 (2006.01)
Patent
CA 1228295
ABSTRACT OF THE DISCLOSURE A device or kit is provided herein for the inhalation administration of an effective amount of a specified pharmaceutical composition. Such pharmaceutical composition includes at least one ganglioside compound, or a pharmaceutically-acceptable salt thereof, or at least one inner ganglioside derivative or a pharmaceutically-acceptable salt thereof, or mixtures thereof. The inner ester ganglioside derivatives comprise: (1) a carbohydrate portion, at least one ceramide and at least one acid moiety, (2) the carbohydrate portion including at least one N-acetylgalactosamine or N- acetylglucosamine moiety and at least one glucose and galactose moiety, (3) the acid moiety including at least one N- acetylneuraminic acid or N-glycolylneuraminic acid, and (4) the carboxyl group of at least one of the acid moieties being ester bonded to a hydroxyl group of one of the carbohydrates or one of the acid moieties to form a lactonic ring. Such pharmaceutical composition also includes a pharmaceutically-acceptable carrier or diluent for the ganglioside compound. The kit also includes as an essential element thereof, a spray device operatively associated with the pharmaceutical composition. Such spray device is operative to spray an effective amount of the pharmaceutical composition to stimulate nerve sprouting.
466641
Della Valle Francesco
Romeo Aurelio
Borden Ladner Gervais Llp
Fidia S.p.a.
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