Kits and methods for assessing oxidative stress

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) C07H 21/00 (2006.01) C12N 15/12 (2006.01)

Patent

CA 2443395

The invention relates to kits and methods for assessing the susceptibility of a human to oxidative stress or damage. The methods involve assessing occurrence in the human's genome of one or more polymorphisms (e.g., single nucleotide polymorphisms) that occur in one or more genes associated with oxidative stress and that are associated with a disorder in humans. Preferred assessment and scoring methods are disclosed, as are kits for performing the methods.

La présente invention concerne des trousses et des méthodes permettant d'évaluer la réceptivité d'un être humain au stress oxydatif ou à ses dommages. Les méthodes décrites dans cette invention consistent à évaluer la présence dans le génome humain d'un ou de plusieurs polymorphismes (par exemple, des polymorphismes de nucléotide simple) apparaissant dans un ou plusieurs gènes associés au stress oxydatif et qui sont associés à un trouble chez les êtres humains. L'invention concerne des méthodes d'évaluation et de calcul privilégiées ainsi que des trousses permettant de mettre en oeuvre ces méthodes.

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