Kluyveromyces as a host strain

Details Kluyveromyces as a host strain Kluyveromyces as a host strain

C - Chemistry, Metallurgy

12

N

195/1.18, 195/1.

C12N 1/16 (2006.01) C07K 14/765 (2006.01) C12N 9/24 (2006.01) C12N 9/34 (2006.01) C12N 9/64 (2006.01) C12N 9/72 (2006.01) C12N 15/14 (2006.01) C12N 15/58 (2006.01) C12N 15/59 (2006.01) C12N 15/62 (2006.01) C12N 15/81 (2006.01)

Patent

CA 1323850

Abstract of the Disclosure Kluyveromyces hosts and DNA expression cassettes for use in Kluyveromyces are provided for transcription of endo- genous and/or exogenous DNA, and production of peptides, for enhancing production of an endogenous product, or producing an exogenous product. The Kluyveromyces hosts find particu- lar use for secretion of a desired peptide product, where signal sequences may be native to the peptide or provided from endogenous or exogenous signal sequences, including synthetic sequences, functional in Kluyveromyces. A trans- formation procedure is provided for efficiently transforming Kluyveromyces.

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