Knock-out animal for taar1 function

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/85 (2006.01) A01K 67/02 (2006.01) A01K 67/027 (2006.01) C12N 5/10 (2006.01) C12N 15/79 (2006.01) C12Q 1/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/567 (2006.01)

Patent

CA 2559880

The present invention relates to a vector construct comprising genomic sequences homologous to upstream and downstream regions flanking the single coding exon of the TAAR1 gene, one or more selection marker genes and optionally a reporter gene and the use thereof. The present invention further provides TAAR1 knock- out animals and the use thereof.

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