Kojic acid derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 309/40 (2006.01) C12N 9/99 (2006.01)

Patent

CA 2135824

ABSTRACT OF THE DISCLOSURE Disclosed herein is novel kojic acid derivatives represented by the following formula (I): Image (I) wherein R1 is a hydrogen atom or hydroxyl group; and R2 is a hydroxyl group. having a strong activity of inhibiting tyrosinase, which is involved in a melanin formation. The compounds of the present invention shows a stronger tyrosinase-inhibiting and radical scavenging activities, and has a low side effects to the human skin.

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