Kruppel-like factor 6 (klf6), a tumor suppressor protein,...

Details Kruppel-like factor 6 (klf6), a tumor suppressor protein,... Kruppel-like factor 6 (klf6), a tumor suppressor protein,...

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2419064

The present invention relates to identification of tumor suppressor activity of a protein, KLF6 (KLF6), and to related diagnostic and therapeutic compositions and methods. The discovery of this tumor suppressor activity provides screening targets as well, particularly screening for compounds that overcome gene inactivation or alteration.

L'invention porte sur l'identification de l'activité de suppression de tumeurs d'une protéine, la KLF6 (KLF6), et sur des compositions et méthodes diagnostiques et thérapeutiques associées. La découverte de cette activité fournit également des cibles de criblage, notamment de criblage de composés qui contrent l'inactivation ou l'altération du gène.

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