Kv6.2, a voltage-gated potassium channel subunit

Details Kv6.2, a voltage-gated potassium channel subunit Kv6.2, a voltage-gated potassium channel subunit

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) A61K 39/395 (2006.01) C07K 14/705 (2006.01)

Patent

CA 2331829

The invention provides isolated nucleic acid and amino acid sequences of Kv6.2, antibodies to Kv6.2, methods of detecting Kv6.2, methods of screening for voltage-gated potassium channel activators and inhibitors using biologically active Kv6.2, and kits for screening for activators and inhibitors of voltage gated potassium channels comprising Kv6.2.

L'invention a pour objet des séquences d'acides aminés et d'acide nucléique isolées de Kv6,2 et des anticorps du Kv6,2. L'invention traite de procédés de détection du Kv6,2, de procédés de détection des activateurs et des inhibiteurs du canal potassique potentiel dépendant à l'aide du Kv6,2 présentant une activité biologique, et des trousses pour détecter les activateurs et les inhibiteurs des canaux potassiques potentiel dépendants comprenant du Kv6,2.

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