L-carnitin dehydrogenases, their derivatives and method for...

Details L-carnitin dehydrogenases, their derivatives and method for... L-carnitin dehydrogenases, their derivatives and method for...

C - Chemistry, Metallurgy

12

P

C12P 41/00 (2006.01) C07D 333/20 (2006.01) C12N 9/04 (2006.01) C12N 15/63 (2006.01) C12P 7/02 (2006.01) C12P 17/00 (2006.01)

Patent

CA 2521288

The invention relates to proteins that have an enzymatic activity for reducing substituted alkanones, such as 3-methylamino-1-(2-thienyl)-propane-1-on. The invention also relates to nucleic acids that encode these proteins, to nucleic acid constructs, vectors, genetically modified microorganisms and to methods for producing substituted (S) alkanols, such as for example (S)-3-methylamino- 1-(2-thienyl)-(S)-propanol.

La présente invention concerne des protéines présentant une activité enzymatique de réduction d'alcanones substitués, par exemple, la 3-méthylamino-1-(2-thiényl)-propan-1-one. L'invention concerne en outre des acides nucléiques codant pour cette protéine, des constructions d'acides nucléiques, des vecteurs, des micro-organismes génétiquement modifiés, ainsi qu'un procédé de production de (S)-alcanols substitués, par exemple de (S)-3-méthylamino-1-(2-thiényl)-(S)-propanol.

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