L-glutamic acid derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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167/222, 260/261

C07D 239/48 (2006.01) A61K 31/505 (2006.01) C07F 7/10 (2006.01)

Patent

CA 2037015

ABSTRACT OF THE DISCLOSURE Substituted pyrimidin-5-yl derivatives of L-glutamic acid are anti-neoplastic agents. A typical embodiment is N- (4- [6-(2,6-diamino-4-hydroxypyrimidin-5-yl)hex-1-en-3- yl]benzoyl}-L-glutamic acid.

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