L-lysine-producing corynebacteria and process for the...

C - Chemistry – Metallurgy – 12 – N

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C12N 1/21 (2006.01) C07K 14/34 (2006.01) C12N 15/31 (2006.01) C12N 15/67 (2006.01) C12N 15/77 (2006.01) C12P 13/08 (2006.01)

Patent

CA 2310890

The invention relates to L-lysine-producing strains of corynebacteria with amplified pyc gene (pyruvate carboxylase gene), in which strains additional genes, chosen from the group comprising the dapA gene (dihydrodipicolinate synthase gene), the lysC gene (aspartate kinase gene), the lysE gene (lysine export carrier gene) and the dapB gene (dihydrodipicolinate reductase gene), but especially the dapA gene, are amplified and, in particular, overexpressed, and to a process for the preparation of L-lysine.

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