L-phenylalanyl-trna synthetase mutants, a process for the...

Details L-phenylalanyl-trna synthetase mutants, a process for the... L-phenylalanyl-trna synthetase mutants, a process for the...

C - Chemistry, Metallurgy

12

N

C12N 15/52 (2006.01) C07K 14/62 (2006.01) C12N 1/21 (2006.01) C12N 9/00 (2006.01)

Patent

CA 2059611

Abstract of the disclosure HOE 91/F 392G L-Phenylalanyl-tRNA synthstase mutants, a process for the preparation thereof and the use thereof for the in vivo incorporation of non-proteinogenous amino acids into peptides or proteins The invention relates to L-phenylalanyl-tRNA synthetases from microorganisms which, by reason of a modification generated by genetic engineering, have an altered sub- strate selectivity, and to their preparation and use for the in vivo incorporation of non-proteinogenous amino acids into peptides or proteins.

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