G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/487 (2006.01)
Patent
CA 2531342
This invention incorporates the use of bioimpedance measurements of intact cells to classify and characterize any unique global cellular event such as signal transduction from ligand/receptor interactions, cytotoxicity, apoptosis, tumor cell progression, or stem cell differentiation. Specifically, we have demonstrated that this invention can classify signal transduction pathways from G-protein coupled, tyrosine kinase, and nuclear receptors.
L'invention concerne l'utilisation de mesures de bioimpédance de cellules intactes pour classifier et pour caractériser un événement cellulaire global unique quelconque, notamment une transduction de signal à partir d'interactions ligand/récepteur, la cytotoxicité, l'apoptose, la progression cellulaire tumorale ou la différenciation de cellules souches. En particulier, cette invention permet de classifier des trajectoires de transduction de signal à partir de récepteurs nucléaires et d'une tyrosine kinase couplée à une protéine G.
Fuller Chris
Liu Vivian
Pitchford Simon
Verdonk Ed
Dh Technologies Development Pte. Ltd.
Mds Inc.
Torys Llp
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