Labeled derivatives of cyclosporins

Details Labeled derivatives of cyclosporins Labeled derivatives of cyclosporins

C - Chemistry, Metallurgy

07

K

530/7.64

C07K 7/64 (2006.01)

Patent

CA 1338653

The present invention relates generally to monoclonal antibodies to cyclosporins, in particular to monoclonal antibodies capable of distinguishing between cyclosporins and metabolites thereof and suitable for use in diagnostic/assay kits, as well as to novel hybridoma cell lines used in the production of said monoclonal antibodies and diagnostic/assay kits comprising said monoclonal antibodies. In particular the invention relates to novel cyclosporins and immunogenic conjugates comprising them, used for the generation of monoclonal antibodies as aforesaid and also useful for the generation of regular polyclonal antisera suitable for diagnostic/assay kit use, as well as to the product antisera and antibodies and diagnostic/assay kits comprising them.

615677

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