Labeled hydantoin conjugate and its use in analytical...

G - Physics – 01 – N

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G01N 33/532 (2006.01) G01N 33/535 (2006.01) G01N 33/94 (2006.01)

Patent

CA 1262526

-0- LABELED HYDANTOIN CONJUGATE AND ITS USE IN ANALYTICAL ELEMENT AND IMMUNOASSAYS Abstract of the Disclosure A heterogeneous, competitive binding im- munoassay for either phenytoin or phenobarbital is conducted with a labeled conjugate comprising a derivative of hydantoin and a label. The hydantoin derivative is 5-ethyl, 5-phenyl hydantoin and it is linked to the label (e.g. an enzyme) with a linkage derived from an aliphatic monocarboxylic acid. The immunoassay can be carried out either in solution or with a dry analytical element.

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