Labeled macrophage scavenger receptor antagonists for...

Details Labeled macrophage scavenger receptor antagonists for... Labeled macrophage scavenger receptor antagonists for...

C - Chemistry, Metallurgy

07

F

C07F 13/00 (2006.01) A61K 51/04 (2006.01) C07F 1/08 (2006.01)

Patent

CA 2438174

Detectably labeled macrophage scavenger receptor antagonists useful for the diagnosis and monitoring of various cardiovascular diseases including but not limited to atherosclerosis, vulnerable plaque, coronary artery disease, renal disease, thrombosis, transient ischemia due to clotting, stroke, myocardial infarction, organ transplant, organ failure and hypercholesterolemia.

L'invention concerne des antagonistes des récepteurs éboueurs des macrophages marqués de manière détectable, utiles pour le diagnostic et la surveillance de diverses maladies cardiovasculaires parmi lesquelles figurent notamment l'athérosclérose, la plaque vulnérable, la coronaropathie, l'affection rénale, la thrombose, l'ischémie transitoire associée à une coagulation, l'apoplexie, l'infarctus du myocarde, une transplantation, une défaillance d'organe et l'hypercholestérolémie.

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