A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 51/04 (2006.01) A61K 49/00 (2006.01) C07B 59/00 (2006.01) C07C 323/58 (2006.01)
Patent
CA 2759000
Imaging agents that comprise labeled substrates of the cystine/glutamate antiporter of cells, whereby the methods of use comprise introducing the labeled agents into cells via the cystine/glutamate antiporter, which are then reduced to a labeled cysteine, and subsequently detected in the cell.
La présente invention concerne des agents d'imagerie qui comprennent des substrats marqués de l'antiporteur cystine/glutamate des cellules, leurs méthodes d'utilisation consistant à faire entrer les agents marqués dans les cellules grâce à l'antiporteur cystine/glutamate. Lesdits agents marqués sont ensuite réduits en cystéine marquée, et par la suite détectés dans la cellule.
Amarasinghe Kande Kankanamalage Dayara
Huntington Jennifer
Lee Brian Duh-Lan
Schaffer Paul
Syud Faisal Ahmed
Company General Electric
Fetherstonhaugh & Co.
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