Labeling of target molecules, identification of organelles...

C - Chemistry – Metallurgy – 07 – F

Patent

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Details

C07F 9/6558 (2006.01) C07D 277/64 (2006.01) C07D 417/06 (2006.01) C07D 417/14 (2006.01) C07F 9/58 (2006.01) C07F 9/60 (2006.01) C07F 9/6541 (2006.01) G01N 33/52 (2006.01)

Patent

CA 2745799

The present invention provides dyes, reactive dyes and labeled reagents that may be used in the detection or quantification of desirable target molecules, such as proteins, nucleic acids and cellular organelles. Dyes are provided that may be used free in solution where the binding of the dye to the target molecule provides signal generation. Dyes are also provided that comprise reactive groups that may be used to attach the dyes to probes that will bind to desirable target molecules. The novel dyes of the present invention have been modified to provide beneficial properties.

La présente invention porte sur des colorants, des colorants réactifs et des réactifs marqués qui peuvent être utilisés dans la détection ou la quantification de molécules cibles souhaitées, telles que des protéines, des acides nucléiques et des organelles cellulaires. Les colorants de l'invention peuvent être utilisés libres en solution, la liaison du colorant à la molécule cible permettant la génération d'un signal. L'invention porte également sur des colorants qui comprennent des groupes réactifs qui peuvent être utilisés pour attacher les colorants à des sondes qui se lieront à des molécules cibles souhaitées. Les nouveaux colorants de la présente invention ont été modifiés pour fournir des propriétés utiles.

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