C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 13/04 (2006.01) A61K 51/04 (2006.01) C07B 59/00 (2006.01) C07C 229/24 (2006.01) C07C 229/26 (2006.01) C07C 237/06 (2006.01) C07C 255/28 (2006.01) C07K 2/00 (2006.01)
Patent
CA 2172455
The present Invention provides a labelled .beta.-cyano-L-alanine and a .gamma.-cyano-.alpha.-aminobutyric acid, of which cyano group carbon is labelled with radionuclids 11C or 14C, or stable isotope 13C. The present invention also provides a labelled amino acids such as asparagine, asparatic acid, DABA, GABA, glutamine and glutamic acid synthesized by using the labelled .beta.-cyano-L-alanine and the .gamma.-cyano-.alpha.-aminobutyric acid as an intermediate. The labelled amino acids are useful for in vivo imaging of tumors and brain functions.
Antoni Gunnar
Furuya Yuji
Langstrom Bengt
Omura Hironori
Watanabe Yasuyoshi
Furuya Yuji
Japan Science And Technology Corporation
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Omura Hironori
Research Development Corporation Of Japan
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