Labelled fibrinogen receptor antagonists, the use thereof...

Details Labelled fibrinogen receptor antagonists, the use thereof... Labelled fibrinogen receptor antagonists, the use thereof...

C - Chemistry, Metallurgy

07

B

C07B 59/00 (2006.01) C07C 255/53 (2006.01) C07C 257/18 (2006.01) C07D 207/26 (2006.01) C07D 207/267 (2006.01) C07D 211/34 (2006.01) C07D 233/30 (2006.01) C07D 233/32 (2006.01) C07D 233/72 (2006.01) C07D 235/12 (2006.01) C07D 235/18 (2006.01) C07D 249/12 (2006.01) C07D 285/10 (2006.01) C07D 401/12 (2006.01) C07D 403/02 (2006.01) C07D 403/04 (2006.01) G01N 33/534 (2006.01) G01N 33/567 (2006.01)

Patent

CA 2094963

Abstract Fibrinogen Receptor Antagonists The invention relates to new labelled fibrinogen receptor antagonists having a receptor affinity comparable to or greater than that of 125I-fibrinogen and whose binding is not disrupted by foreign proteins, more particularly to tritium-labelled fibrinogen receptor antagonists as claimed in claim 3, which have a receptor affinity (K?) of less than 500 nM in the presence of foreign protein, and their use as ligands in the fibrinogen receptor binding test or for determining the concentration of fibrinogen receptor antagonists.

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