Labelled, modified oligonucleotides

C - Chemistry – Metallurgy – 07 – H

Patent

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Details

C07H 21/00 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) A61K 51/04 (2006.01) A61K 51/10 (2006.01)

Patent

CA 2057292

Abstract The invention relates to novel labelled modified oligonucleotides useful for gene therapy, a conjugate of a targeting moiety, such as an antibody and a modified oligonucleotide complementary to the labelled oligonucleotide, the combination of both being useful in therapy of viral infections, tumours and (auto) immunodiseases. Also disclosed are pharmaceutical formalations comprising the various compounds.

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