G - Physics – 01 – T
Patent
G - Physics
01
T
167/48
G01T 1/164 (2006.01) A61K 51/12 (2006.01)
Patent
CA 1100871
Labelled Phospholipid Spheres for Organ Visualization ABSTRACT OF THE DISCLOSURE A carrier is disclosed for diagnostic scanning agents labelled with short-lived radioisotopes for medical organ studies which comprises colloidally dispersed phospholipid material, and also disclosed are new diagnostic scanning agents utilizing the carrier and a radioisotope, preferably 99mTc, which is in a form which complexes with the carrier. The radioisotope labelling can be carried out directly before use, the carrier in dispersed form being stable for a considerable period of time. Methods of preparation of the scanning agents are also disclosed which provide a material which localizes mainly in the liver after injection, or alternately at least intially in the lungs when an aggregating agent is used during preparation in a specific sequence of steps. Specific organ scans or sequential scanning is thus possible.
241628
Petkau Abram
Pleskach Stanley D.
Borden Ladner Gervais Llp
Her Majesty In Right Of Canada As Represented By Atomic Energy O
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