C - Chemistry – Metallurgy – 07 – B
Patent
C - Chemistry, Metallurgy
07
B
260/297.3, 260/6
C07B 59/00 (2006.01) C07C 15/18 (2006.01) C07C 101/04 (1985.01)
Patent
CA 1236483
ABSTRACT A process for isotopically labelling certain chemical compounds, with a selected or desired isotopic label comprising first treating a precursor material with the isotopic material to exchange the hydrogen atoms of the precursor material with the isotopic material and then or simultaneously reacting the exchanged precursor with a chemical compound so as to label the chemical compound with the isotopic material at a desired preselected location within the molecule of the chemical compound. A typical example involves first forming deuterated Raney nickel and then reacting the deuterated Raney nickel with an organic compound under relatively mild conditions so that specific selective hydrogen-deuterium exchange occurs within the molecules of the chemical compound at a pre-selected location within the molecule.
476816
Commonwealth Of Australia (the)
Ridout & Maybee Llp
LandOfFree
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