Lacrimal gland specific emulsions for topical application to...

Details Lacrimal gland specific emulsions for topical application to... Lacrimal gland specific emulsions for topical application to...

A - Human Necessities

61

K

A61K 38/13 (2006.01) A61K 9/107 (2006.01) A61K 47/30 (2006.01)

Patent

CA 2309033

A pharmaceutical composition is disclosed in the form of a nonirritating emulsion which includes at least one cyclosporin in admixture with a higher fatty acid glyceride and polysorbate 80. More particularly, the cyclosporin may be cyclosporin A and the higher fatty acid glyceride may be castor oil. Composition has been found to be of a high comfort level and low irritation potential suitable for delivery of medications to sensitive areas such as ocular tissues with enhanced absorption in the lacrimal gland. In addition, the composition has stability for up to nine months without crystallization of cyclosporin.

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