Lactam compounds and methods of using the same

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 471/10 (2006.01) A61K 31/438 (2006.01)

Patent

CA 2630492

The present invention relates to inhibitors of 11-.beta. hydroxyl steroid dehydrogenase type 1 and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-.beta. hydroxyl steroid dehydrogenase type 1.

La présente invention concerne des inhibiteurs de 11-.beta.-hydroxylstéroïde déshydrogénase de type 1 et des compositions pharmaceutiques de ceux-ci. Les composés de l'invention peuvent être utiles dans le traitement de différentes maladies associées à l'expression ou l'activité de la 11-.beta.-hydroxylstéroïde déshydrogénase de type 1.

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