Lactam inhibitors of fxa and method

Details Lactam inhibitors of fxa and method Lactam inhibitors of fxa and method

C - Chemistry, Metallurgy

07

D

C07D 223/06 (2006.01) A61K 31/4427 (2006.01) A61K 31/496 (2006.01) A61K 31/55 (2006.01) C07D 401/02 (2006.01) C07D 403/02 (2006.01) C07K 5/06 (2006.01) C07K 5/078 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2361919

Lactam inhibitors are provided which have structure (I) wherein X is (2) or (3), Y is O or S and R4 is (4), R7O- or R8, and R1, R2, R3, R5, R6, R7, and R8, are as defined herein. These compounds are inhibitors of Factor Xa and thus are useful as anticoagulants. A method for treating cardiovascular diseases associated with thromboses is also provided.

L'invention concerne des inhibiteurs lactame représentés par la formule (I) dans laquelle X représente (2) ou (3), Y représente O ou S et R?4¿ représente (4), R?7¿O- ou R?8¿, et R?1¿, R?2¿, R?3¿, R?4¿, R?5¿, R?6¿, R?7¿ et R?8¿ sont tels que définis dans cette invention. Ces composés sont des inhibiteurs du facteur Xa et sont ainsi d'utiles anticoagulants. L'invention concerne également une méthode de traitement des maladies cardio-vasculaires associées aux thromboses.

Affiliated with

Also associated with

Rating

Lactam inhibitors of fxa and method does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Lactam inhibitors of fxa and method, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Lactam inhibitors of fxa and method will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1583854