Lactate dehydrogenase mutants of streptococcus mutans

Details Lactate dehydrogenase mutants of streptococcus mutans Lactate dehydrogenase mutants of streptococcus mutans

C - Chemistry, Metallurgy

12

N

167/318, 195/34.

C12N 15/00 (2006.01) A61K 8/66 (2006.01) A61K 35/74 (2006.01) A61K 45/00 (2006.01) A61Q 11/00 (2006.01)

Patent

CA 1152014

CHL-41 LACTATE DEHYDROGENASE MUTANTS OF STREPTOCOCCUS MUTANS ABSTRACT OF THE DISCLOSURE Mutant strains have been isolated from Streptococcus mutans strain BHT-2(str) which are characterized by a single point mutation in the struc- tural gene for the enzyme, L(+) lactate dehydrogenase, this enzyme being normally responsible for lactic acid production by this bacterium. Strepto- coccus mutans is believed to be a principal pathogen in dental caries, a disease characterized by the dissolution of the mineral portion of the tooth caused by acid resulting from the interaction of bacteria on the tooth surface with carbohydrates. The mutant strains of the invention will be found useful as prototype nonvirulent effector strains in controlling the incidence and severity of dental caries.

322198

Affiliated with

Also associated with

Rating

Lactate dehydrogenase mutants of streptococcus mutans does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Lactate dehydrogenase mutants of streptococcus mutans, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Lactate dehydrogenase mutants of streptococcus mutans will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-263441