Lactic acid bacteria comprising unmethylated...

Details Lactic acid bacteria comprising unmethylated... Lactic acid bacteria comprising unmethylated...

A - Human Necessities

61

K

A61K 35/74 (2006.01) A61K 38/19 (2006.01) A61P 17/02 (2006.01) A61P 29/00 (2006.01) A61P 37/02 (2006.01)

Patent

CA 2457092

(A) methods of preventing/treating (i) inflammatory conditions (ii) autoimmune disorders (iii) reducing apoptosis (iv) reducing caspases (v) treating fistulas/wounds; by administering compositions comprising lactic acid bacteria containing unmethylated cytosine-guanine dinucleotides, e.g. Lactobacillus acidophilus: (B) compositions for preventing/treating inflammatory conditions comprising lactic acid bacteria containing unmethylated sphingomyelinase.

Des bactéries lactiques renfermant le cytosine-guanine (CpG) dinucléotide non méthylé sont utilisées pour produire un effet positif sur la réponse immunitaire chez un sujet présentant ou susceptible de présenter une réponse inflammatoire aux lipopolysaccharides.

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