Lactic acid bacterial suppressor mutants and their use as...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/74 (2006.01) A21D 8/04 (2006.01) A23B 4/22 (2006.01) A23B 7/155 (2006.01) A23C 9/127 (2006.01) C12N 1/21 (2006.01) C12N 15/68 (2006.01)

Patent

CA 2160166

Useful mutants of lactic acid bacteria or plasmids capable of replicating in lactic acid bacteria, comprising nonsense mutation suppressor-encoding genes are disclosed. The use of such nonsense mutation suppressor encoding genes for confining a replicon to a specific lactic acid bacterium or to a lactic acid bacterium growing in a particular environment and for controlling the number of lactic acid bacterial cells in a particular environment is also disclosed.

Mutants utiles de bactéries d'acide lactique ou plasmides capables de se répliquer dans des bactéries d'acide lactique et comprenant des gènes codant un suppresseur de mutation non-sens. L'invention se rapporte également à l'utilisation de ces gènes suppresseurs pour confiner un réplicon à une bactérie d'acide lactique spécifique ou à une bactérie d'acide lactique croissant dans un environnement particulier, et pour réguler le nombre de cellules bactériennes d'acide lactique dans un environnement particulier.

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