Lactic acid bacterium having high oxalic acid decomposition...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 1/20 (2006.01) A23L 1/30 (2006.01) A61K 35/74 (2006.01) A61P 3/00 (2006.01) A61P 7/06 (2006.01) A61P 13/04 (2006.01) A61P 13/12 (2006.01) A61P 19/10 (2006.01)

Patent

CA 2739345

Disclosed is a lactic acid bacterium having a higher oxalic acid decomposition activity by several times than those of lactic acid bacteria which are known to have an oxalic acid decomposition activity. Also disclosed is use of the lactic acid bacterium. A lactic acid bacterium capable of decomposing a large quantity of oxalic acid is screened from Lactobacillus strain 132 lactic acid bacteria which have been uniquely isolated from feces or gastric juices from adult human bodies. As a result, a lactic acid bacterium can be discovered which has an oxalic acid decomposition rate of 50% or more when the lactic acid bacterium is cultured in a culture medium supplemented with 10 mM of oxalic acid at 37°C for 72 hours in which the culture is started at the initial pH value of 6.5.

Cette invention concerne une bactérie de l'acide lactique ayant une activité de décomposition de l'acide oxalique plusieurs fois supérieure à celle des bactéries de l'acide lactique connues pour avoir une activité de décomposition de l'acide oxalique. L'utilisation de ladite bactérie de l'acide lactique est également décrite. Une bactérie de l'acide lactique capable de décomposer une grande quantité d'acide oxalique, Lactobacillus souche 132, est identifiée par criblage des bactéries de l'acide lactique qui ont été isolées uniquement à partir des selles ou des sucs gastriques de corps humains adultes. On a pu ainsi découvrir une bactérie de l'acide lactique ayant un taux de décomposition de l'acide oxalique supérieur ou égal à 50 % quand ladite bactérie de l'acide lactique est cultivée dans un milieu de culture additionné de 10 mM d'acide oxalique à 37 °C pendant 72 heures et quand la culture démarre à la valeur de pH initiale de 6,5.

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