Laminate device for controlled and prolonged release of...

Details Laminate device for controlled and prolonged release of... Laminate device for controlled and prolonged release of...

A - Human Necessities

61

K

43/105, 167/165,

A61K 9/70 (2006.01) A01N 25/34 (2006.01) A61K 9/22 (2006.01) A61M 31/00 (2006.01)

Patent

CA 1237982

LAMINATE DEVICE FOR CONTROLLED AND PROLONGED RELEASE OF SUBSTANCES TO AN AMBIENT ENVIRONMENT Abstract Laminate device for the controlled and prolonged release of at least one active agent to an ambient environment comprising at least one core sheet, said core sheet or sheets comprising said agent or agents in a polymer matrix, and, in a preferred embodiment, a porosity enhancing agent in admixture with said agent; said core sheet or sheets being alternately sandwiched or interposed between coextensive inert polymeric films substantially impermeable to said environment and to said agent or agents, said device being perforated by one or a plurality of macroholes ex- tending through said sheets and said films. In a modification of said device the perimeter edge thereof is coated by an inert polymeric film substantially impermeable to said environment and to said agent or agents. Also included are methods for making such a device.

473649

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