C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 253/065 (2006.01) A61K 51/08 (2006.01) A61K 51/10 (2006.01) A61P 43/00 (2006.01)
Patent
CA 2586474
Generally, the present invention relates to lamotrigine analogs that have substituents at the triazine 3-position and on the benzene 4-position and 5- position. The lamotrigine analogs can include immunogenic moieties that can be used to prepare anti-lamotrigine antibodies, or antigenic moieties that can be used in immunodiagnostic assays for lamotrigine. Also, the lamotrigine analog can include tracer moieties for detecting the presence or amount of the analog during an immunodiagnostic assay. Additionally, the lamotrigine analogs can be used in immunodiagnostic assays to compete with lamotrigine for binding with anti-lamotrigine antibodies.
L'invention concerne de manière générale des analogues de lamotrigine qui présentent des substituants dans la position 3 triazine et dans les positions 4 et 5 benzène. Les analogues de lamotrigine peuvent contenir des fractions immunogéniques qui peuvent servir dans la préparation d'anticorps anti-lamotrigine, ou des fractions antigéniques pouvant servir dans des épreuves immunodiagnostiques de la lamotrigine. Par ailleurs, l'analogue de lamotrigine peut contenir des fractions traceur pour détecter la présence ou la quantité de l'analogue au cours d'une épreuve immunodiagnostique. De plus, les analogues de lamotrigine peuvent servir dans des épreuves immunodiagnostiques pour s'opposer à la lamotrigine et se lier aux anticorps anti-lamotrigine.
Arabshahi Lili
Ouyang Anlong
Roberts Mark
Cassan Maclean
Seradyn Inc.
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