A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/16 (2006.01) A61K 9/72 (2006.01)
Patent
CA 2383491
Particles having a tap density less than about 0.4 g/cm3 are formed by spray drying from a colloidal solution including a carboxylic acid or salt thereof, a phospholipid, a divalent salt and a solvent such as an aqueous-organic solvent. The colloidal solution can also include a therapeutic, prophylactic or diagnostic agent. Preferred carboxylic acids include at least two carboxyl groups. Preferred phospholipids include phosphatidylcholines, phosphatidylethanolamines, phosphatidylglycerols, phophAtidylserines, phosphatidylinositols and combinations thereof. The particles are suitable for pulmonary delivery.
L'invention se rapporte à des particules dont la masse volumique après tassement est inférieure à 0,4 g/cm?3¿ environ, formées par séchage par atomisation à partir d'une solution colloïdale comprenant un acide carboxylique ou un sel de celui-ci, un phospholipide, un sel divalent et un solvant tel qu'un solvant aqueux-organique. Cette solution colloïdale peut également comprendre un agent thérapeutique, prophylactique ou diagnostique. Les acides carboxyliques préférés comprennent au moins deux groupes carboxyle. Les phospholipides préférés comprennent les phosphatidylcholines, les phosphatidyléthanolamines, les phosphatidylglycérols, les phophatidylsérines, les phosphatidylinositols et des combinaisons de ceux-ci. Ces particules se prêtent à une administration par voie pulmonaire.
Batycky Richard P.
Caponetti Giovanni
Lipp Michael M.
Advanced Inhalation Research Inc.
Gowling Lafleur Henderson Llp
LandOfFree
Large porous particles by spray-drying does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Large porous particles by spray-drying, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Large porous particles by spray-drying will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1793126