Large scale production of plasminogen activator from normal...

Details Large scale production of plasminogen activator from normal... Large scale production of plasminogen activator from normal...

C - Chemistry, Metallurgy

12

N

195/127, 195/78

C12N 9/64 (2006.01) C08B 37/00 (2006.01) C12N 9/72 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1282726

07-21(352)A LARGE SCALE PRODUCTION OF PLASMINOGEN ACTIVATOR FROM NORMAL HUMAN COLON CELLS Abstract of the Disclosure Plasminogen activators (PA) are obtained from cultured normal human colon cells which are adaptable to large scale production. A purified tissue PA (t-PA) is obtained from CGD-18Co normal human colon fibroblast cells which shows chemical differences from Bowes melanoma t-PA. By: Joseph Feder, Nicholaos K. Harakas, Jon P. Schaumann, Daniel T. Connolly, and Arthur J. Wittwer.

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