Large substituent, non-phenolic opioids

Details Large substituent, non-phenolic opioids Large substituent, non-phenolic opioids

C - Chemistry, Metallurgy

07

D

C07D 221/26 (2006.01) A61K 31/485 (2006.01) A61P 25/04 (2006.01) A61P 25/36 (2006.01) C07D 221/28 (2006.01) C07D 489/00 (2006.01) C07D 489/12 (2006.01)

Patent

CA 2615774

8-Substituted-2,6-methano-3-benzazocines of general structure; formula (I) are useful as analgesics, anti-diarrheal agents, anticonvulsants, antitussives and anti- addiction medications. One embodiment is the subgenus of biphenylethyl compounds; formula (II).

La présente invention a trait à des 2,6-méthano-3-benzazocines substituées en position 8 de formule générale (I) utiles en tant qu'analgésiques, agents anti-diarrhée, agents anticonvulsants, et médicaments antitussifs et anti-accoutumance. Un mode de réalisation est constitué par le sous-genre de composés biphényléthyle de formule (II).

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