Laser radiation desorption device for manipulating a liquid...

B - Operations – Transporting – 01 – L

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Details

B01L 3/00 (2006.01) B01F 13/00 (2006.01) F04B 19/00 (2006.01)

Patent

CA 2569256

The invention relates to an integrated system for microfluidic analysis of a liquid sample comprising a liquid sample preparing means (100) which is provided with a displacement means (101) for introducing the sample and reagents and for transmitting said sample and reagents to a second means (200) for chemically or biochemically treating the liquid sample drops, wherein said treating means comprises also means (201) for displacing sample drops to means (300) for drop analysis. Said invention is particularly suitable for a laser radiation desorption device comprising a system for manipulating the sample and reagents in the form of drops, which is provided with one or several loading posts, one or several transport paths consisting of interdigitated electrodes, one or several chemical or biochemical treatment areas and at least one system for switching to a conductive post on which a laser radiation desorption can be carried out.

L'invention concerne un système intégré d'analyse microfluidique d'un échantillon de liquide comprenant un moyen (100) de préparation de l'échantillon de liquide, lui-même comprenant un moyen (101) de déplacement pour l'introduction de l'échantillon et de réactifs puis leur migration vers un deuxième moyen (200) de traitement chimique ou biochimique de gouttes de l'échantillon de liquide, ce moyen de traitement comprenant également un moyen (201) de déplacement des gouttes de l'échantillon puis leur migration vers un moyen (300) d'analyse des gouttes. L'invention trouve en particulier son application pour un dispositif de désorption par rayonnement laser comprenant un système de manipulation d'un échantillon et de réactifs sous forme de gouttes, avec un ou plusieurs plots de chargement, une ou plusieurs pistes de transport composées d'électrodes interdigitées, une ou plusieurs zones de traitement chimique ou biochimique et au moins un système d'aiguillage vers au moins un plot conducteur sur lequel une désorption par rayonnement laser peut être réalisée.

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