C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/078 (2010.01) C12N 1/20 (2006.01) C12Q 1/02 (2006.01) G01N 33/15 (2006.01)
Patent
CA 2689741
Provided herein is an in vitro granuloma model and methods of its use. Methods of detecting and/or diagnosing latent tuberculosis in a subject are also provided, as are latency-specific antigens (and antibodies thereto), such as .alpha.-crystallin, and methods of identifying and using such molecules. Also provided are immunostimulatory compositions, for instance for use in eliciting an immune response in a subject, such as an immune response to a latent tuberculosis infection. Kits for carrying out the provided methods are also described.
Beall David S.
Birkness Kristin A.
Deslauriers Manon
King Peter
Quinn Frederick D.
Smart & Biggar
The Government Of The United States Of America As Represented By Centers For Disea
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