G - Physics – 01 – N
Patent
G - Physics
01
N
167/37
G01N 33/558 (2006.01) G01N 33/543 (2006.01) G01N 37/00 (2006.01)
Patent
CA 1313616
-60- Abstract A method and apparatus for conducting specific binding pair assays, such as immunoassays, is described. A porous membrane capable of non-bibulous lateral flow is used as assay substrate; a member of the binding pair is affixed in an indicator zone defined in the substrate. The sample is applied at a position distant from the indi- cator zone and permitted to flow laterally through the zone; any analyte in the sample is complexed by the af- fixed specific binding member, and detected. A novel method of detection employs entrapment of observable particle in the complex. Blood is a particularly pre- ferred sample as the red blood cells can be used as the observable particles for detection of the complex.
568070
Eisinger Robert W.
Katz David H.
Khalil Mohammed M.
Sargeant Robert B.
Ade & Company
Quidel
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