Latex for immobilization of physiologically active substance...

C - Chemistry – Metallurgy – 08 – F

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167/153, 195/40,

C08F 212/04 (2006.01) A61K 47/00 (2006.01) C12N 11/08 (2006.01) G01N 33/543 (2006.01) G01N 33/546 (2006.01)

Patent

CA 1301647

NO2-49949C/HO/88 ABSTRACT OF THE DISCLOSURE A latex for immobilization of a physiologically active substance and a latex reagent using the latex are disclosed. The latex is prepared by copolymerizing a mono- mer mixture comprising: (a) 100 parts by weight of an aromatic vinyl monomer; (b) 0.01 to 5 parts by weight of a vinyl monomer having a sulfonic acid group; (c) 1 to 20 parts by weight of an .alpha.,.beta.-unsaturated car- boxylic acid monomer; and (d) 0.05 to 5 parts by weight of a polyfunctional monomer for internal cross-linking; in water using a water-soluble radical polymerization initi- ator in the absence of an emulsifying agent.

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