Lawsonia intracellularis of european origin and vaccines,...

A - Human Necessities – 61 – K

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A61K 39/02 (2006.01) C12N 1/20 (2006.01)

Patent

CA 2533559

The present invention relates to <i>Lawsonia intracellularis</i> vaccines and methods for protecting against and diagnosing <i>L. intracellularis</i> infection. The products and processes of the invention are attainable, in part, as the result of an improved method for cultivating large scale supplies of <i>L. intracellularis</i>, including both a novel isolate of <i>L. intracellularis</i> of European origin and a method of preparing a lyophilized product containing the attenuated European isolate as vaccine product.

La présente invention concerne des vaccins contre <i>Lawsonia intracellularis</i> et des procédés de diagnostic et de protection contre l'infection par <i>L. intracellularis</i>. Les produits et procédés selon l'invention sont partiellement issus d'un procédé amélioré de culture de <i>L. intracellularis</i> à grande échelle faisant intervenir un nouvel isolat de <i>L. intracellularis</i> d'origine européenne et un procédé de préparation d'un produit lyophilisé contenant l'isolat européen en tant que produit de vaccin.

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