Layered pharmaceutical formulations

Details Layered pharmaceutical formulations Layered pharmaceutical formulations

A - Human Necessities

61

K

A61K 9/24 (2006.01) A61K 31/137 (2006.01) A61K 31/138 (2006.01) A61K 31/155 (2006.01) A61K 31/35 (2006.01) A61K 31/423 (2006.01) A61K 31/485 (2006.01) A61K 31/5513 (2006.01)

Patent

CA 2668884

In one embodiment a layered pharmaceutical formulation includes two or more pharmaceutical layers and an intermediate layer disposed between at least two of the two or more pharmaceutical layers, the intermediate layer configured to dissolve in vivo to thereby leave the two or more pharmaceutical layers substantially intact. In one embodiment, an active pharmaceutical ingredient in at least one of the pharmaceutical layers is selected from bupropion, zonisamide, naltrexone, topiramate, phentermine, metformin, olanzapine and fluoxetine.

Selon une forme d'exécution de cette invention, une formulation pharmaceutique en couches comprend deux couches pharmaceutiques ou plus et une couche intermédiaire placée entre au moins deux desdites couches pharmaceutiques, la couche intermédiaire étant configurée pour se dissoudre in vivo de façon à laisser les couches pharmaceutiques sensiblement intactes. Selon d'autres formes d'exécution, un ingrédient pharmaceutique actif d'au moins une des couches pharmaceutiques est sélectionné parmi: bupropion, zonisamide, naltrexone, topiramate, phentermine, metformine, olanzapine et fluoxétine.

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