A - Human Necessities – 61 – N
Patent
A - Human Necessities
61
N
A61N 1/30 (2006.01) A61K 31/4468 (2006.01) A61K 31/4535 (2006.01) A61K 31/485 (2006.01) A61K 38/26 (2006.01) A61K 38/28 (2006.01)
Patent
CA 2315228
The disclosed invention relates to an improved electrotransport device. The improvement relates to a membrane assembly including a low porosity membrane adhered or sealed to one or two high porosity membranes. The high porosity membranes protect the low porosity membrane from being damaged by components or contaminates on the body surface and/or in the drug reservoir which can lead to undesirable passive flux and/or insufficient iontophoretic flux. As a result, the electrotransport device having the membrane assembly more reliably, precisely, and accurately delivers drug and/or therapeutic agent through the body surface by electrotransport.
L'invention concerne un dispositif perfectionné d'électro-apport. L'amélioration porte sur un ensemble membranes comprenant une membrane faiblement poreuse, collée ou scellée sur une ou deux membranes très poreuses. Les membranes très poreuses protègent la membrane faiblement poreuse de tout endommagement par des constituants ou des contaminants présents sur la surface du corps et/ou dans le réservoir à médicament, lequel endommagement peut conduire à un flux passif non voulu et/ou à un flux insuffisant apporté par ionophorèse. Il en résulte que le dispositif d'électro-apport présentant cet ensemble membranes apporte de manière plus fiable, précise et exacte un médicament et/ou un agent thérapeutique à travers la surface corporelle par électro-apport.
Gyory J. Richard
Haak Ronald P.
Alza Corporation
Smart & Biggar
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