Leader sequence inducing a post-translational modification...

Details Leader sequence inducing a post-translational modification... Leader sequence inducing a post-translational modification...

C - Chemistry, Metallurgy

12

N

530/7.1, 530/15.

C12N 15/63 (2006.01) C07K 14/315 (2006.01) C07K 14/32 (2006.01) C12N 15/10 (2006.01) C12N 15/11 (2006.01) C12N 15/31 (2006.01) C12N 15/62 (2006.01) C12N 15/67 (2006.01) C12N 15/74 (2006.01)

Patent

CA 1339414

The method by which polypeptides having residues other than the 20 common amino acids are made is established. A leader peptide sequence, and its gene, are identified which induce or assist post-translational modifications of Cys, Thr, and Ser in prokaryotes. The leader sequence may be used to induce the presence of covalent bonding sites in polypeptides and can be expressed by either naturally occurring or artificial means.

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