Leafhopper ecdysone receptor nucleic acids, polypeptides,...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) C07K 14/72 (2006.01) C07K 16/28 (2006.01) C12N 15/63 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/567 (2006.01)

Patent

CA 2459827

The present invetion relates to a novel isolated leafhopper ecdysone receptor polypeptide. The invention also realtes to an isolated nucleic acid encoding the leafhopper ecdysone receptor polypeptide, to vectors comprising them and to their uses, in particular in methods for modulating gene eypression in an ecdysone receptor-based gene expression modulation system and methods for identifying molecules that modulate leafhopper ecdysone receptor activity.

L'invention concerne un nouveau polypeptide isolé du récepteur à l'ecdysone de la cicadelle. Cette invention concerne également un acide nucléique isolé codant ce polypeptide du récepteur à l'ecdysone de la cicadelle, des vecteurs comprenant ceux-ci ainsi que leurs utilisations, plus spécifiquement dans des procédés de modulation de l'expression génétique dans un système de modulation d'expression génétique basé sur le récepteur à l'ecdysone et dans des procédés d'identification de molécules qui modulent l'activité du récepteur à l'ecdysone de la cicadelle.

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